Old position: chair of the RDA-COVID19-Epidemiology group.
- summary of a interview at the OPECST (Assemblée Nationale et Sénat); PDF here and Youtube video here
- an interview for the Dauphine alumni newsletter (October 2020 Issue)
– GdT Covid intervention: vidéo here
– Some information on the French Mathematical Society site / CNRS version
The individual immunity plays an important role for the patients’ COVID-19 outcome. We propose in this work a numerical model that describes the interaction between the immune system of the host (patient) and the invading SARS-CoC-2 virus. We discuss two important topics (non-neutralizing antibodies and antibody-depencent enhancement phynomena (ADE) and its consequences for vaccination and secondary infection(s).
This work with Antoine Danchin asks the question of the consequences of a first infection with SARS-CoV-2: does a first infection builds immunity or on the contrary will a second infection be more severe due to ADE mechanisms, what are the likely impact of such a phenomenon.
2020: Lockdown : the forecasts that do not take into account different transmission rates within different types of individuals (general population, medical doctors, etc.) will likely be pessimistic. Mathematical proof here.
The inviduals will likely lockdown early but will not follow the societal lockup prescriptions when the epidemic delines (published in Mathematical Modelling of Natural Phenomena, open access)
Simultaneous experimental validations:
– individuals will lockdown by themselves early (https://arxiv.org/abs/2004.14748)
– individuals will end lockdown early than advised: https://www.huffingtonpost.fr/entry/le-maintien-du-confinement-soutenu-par-moins-dun-francais-sur-deux-sondage-exclusif_fr_5ea3080bc5b6f96398140f82
A short Youtube video (in French) presenting this work: https://www.youtube.com/watch?v=EeZn5LqGTE0
2006/07 paper: with arguments that SARS will return (!!) published in Encyclopaedia of Infectious Diseases, 2007, free version here